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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
49.09
Human Site:
Y397
Identified Species:
77.14
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
Y397
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
Y400
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
Y398
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Dog
Lupus familis
XP_535855
696
78257
Y497
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
Y396
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Rat
Rattus norvegicus
P09217
592
67715
Y395
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
I184
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
G
Chicken
Gallus gallus
XP_417561
606
69931
Y409
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Frog
Xenopus laevis
NP_001084068
588
67442
Y389
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
Y389
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
F446
G
H
C
K
L
A
D
F
G
M
C
K
E
G
I
Honey Bee
Apis mellifera
XP_397273
590
68031
Y390
G
H
V
K
L
T
D
Y
G
M
C
K
E
G
V
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
Y396
G
H
I
K
L
T
D
Y
G
M
C
K
E
N
I
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
I348
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y961
G
H
I
K
I
A
D
Y
G
L
C
K
E
D
M
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
73.3
86.6
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
86.6
100
93.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
0
0
14
0
0
0
0
0
0
% A
% Cys:
0
14
7
0
0
0
0
0
0
0
87
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
87
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
14
0
87
0
0
% E
% Phe:
14
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
87
0
14
0
0
0
0
0
87
0
0
0
0
74
14
% G
% His:
0
87
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
74
0
7
0
0
14
0
0
0
14
0
0
14
% I
% Lys:
0
0
0
87
0
0
0
0
0
0
0
87
0
0
0
% K
% Leu:
0
0
0
0
80
0
0
0
0
7
0
0
14
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
14
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
14
0
0
0
0
14
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
14
0
74
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _